Could a B-1 cell derived phagocyte "be one" of the peritoneal macrophages during LPS-driven inflammation?
The inflammatory response is driven by signals that recruit and elicit immune cells to areas of tissue damage or infection.The concept of a mononuclear phagocyte system postulates that monocytes circulating in the bloodstream are recruited to inflamed tissues where they give rise to macrophages.A recent publication demonstrated that the large incre